Selected publications from the Brewer-Raghu lab
Feng, W., Bachant, J., Collingwood, D., Raghuraman, M.K., and Brewer, B.J. (2009). Centromere replication timing determines different forms of genomic instability in Saccharomyces cerevisiae checkpoint mutants during replication stress. Genetics, In Press.
Di Rienzi, S., Collingwood, D., Raghuraman, M.K., and Brewer, B.J. (2009). Fragile Genomic Sites are Associated with Origins of Replication. Genome Biology and Evolution, epub.
McCune, H.J., Danielson, L.S., Alvino, G.M., Collingwood, D., Delrow, J.J., Fangman, W.L., Brewer, B.J., and Raghuraman, M.K. (2008). The Temporal Program of Chromosome Replication: Genomewide Replication in clb5∆ Saccharomyces cerevisiae. Genetics 180:1833-1847.
Data supplement to McCune et al., 2008.
Alvino, G.M., Collingwood, D., Murphy, J.M., Delrow, J., Brewer, B.J., and Raghuraman, M.K. (2007). Replication in hydroxyurea: it's a matter of time. Mol Cell Biol 27:6396-6406.
Data supplement to Alvino et al., 2007.
Feng, W., Collingwood, D., Boeck, M.E., Fox, L.A., Alvino, G.M., Fangman, W.L., Raghuraman, M.K., and Brewer, B.J. (2006). Genomic mapping of single-stranded DNA in hydroxyurea-challenged yeasts identifies origins of replication. Nat Cell Biol 8:148-155.
Raghuraman, M.K., Winzeler, E.A., Collingwood, D., Hunt, S., Wodicka, L., Conway, A., Lockhart, D.J., Davis, R.W., Brewer, B.J., and Fangman, W.L. (2001). Replication dynamics of the yeast genome. Science 294:115-121.
Data supplement to Raghuraman et al., 2001:
Raw data files
Pooled HL data (unsmoothed)
Pooled HL data (smoothed)
Trep data (smoothed)
Origin predictions
Replication profiles (pdf)